Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.50 |
| ▸ | CA1 | P00915 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 7/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530536 | 0.83 | CA2 (0.38) | CA2CA1CA9CA12PTGES2 | |
| SCHEMBL6532201 | 0.82 | POLB (0.42) | CA2CA1L3MBTL1 | |
| SCHEMBL6026242 | 0.79 | PTGES2 (0.35) | CA2CA1CA9CA12PTGES2 | |
| SCHEMBL6025521 | 0.78 | KMT2A (0.42) | CA2CA9L3MBTL1 | |
| SCHEMBL6025786 | 0.77 | PTGES2 (0.38) | CA2CA1CA9CA12PTGES2 | |
| SCHEMBL3661739 | 0.76 | CA2 (0.56) | CA2CA1CA9CA12PTGES2 | |
| SCHEMBL7144287 | 0.76 | CA2 (0.49) | CA2CA1CA9CA12PTGES2 | |
| SCHEMBL6526600 | 0.75 | CA2 (0.53) | CA2CA1CA9CA12PTGES2 | |
| SCHEMBL7354878 | 0.74 | CA2 (0.59) | CA2CA1CA9CA12PTGES2 | |
| SCHEMBL25465864 | 0.72 | CA2 (0.55) | CA2CA1CA9CA12PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |