Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526602 | 0.82 | CA2 (0.50) | CA1CA2L3MBTL1 | |
| SCHEMBL6025521 | 0.78 | KMT2A (0.42) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL6532196 | 0.72 | LMNA (0.39) | POLBMEN1KMT2AMAPTPKM | |
| SCHEMBL6026291 | 0.72 | KMT2A (0.41) | POLBMEN1KMT2AMAPTPKM | |
| SCHEMBL6531288 | 0.71 | MEN1 (0.40) | POLBMEN1KMT2AMAPTPKM | |
| SCHEMBL6025786 | 0.71 | PTGES2 (0.38) | CA1CA2 | |
| SCHEMBL6530536 | 0.70 | CA2 (0.38) | ALDH1A1LMNAHPGDCA1CA2 | |
| SCHEMBL6026242 | 0.68 | PTGES2 (0.35) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6530527 | 0.66 | KMT2A (0.41) | POLBMEN1KMT2AMAPTPKM | |
| SCHEMBL6121414 | 0.66 | CA2 (0.44) | POLBMAPTALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |