Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 12/20 | 0.33 |
| ▸ | CA1 | P00915 | 12/20 | 0.33 |
| ▸ | CA2 | P00918 | 12/20 | 0.33 |
| ▸ | CA4 | P22748 | 11/20 | 0.33 |
| ▸ | CA9 | Q16790 | 11/20 | 0.33 |
| ▸ | CA7 | P43166 | 11/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 11/20 | 0.33 |
| ▸ | CA3 | P07451 | 10/20 | 0.33 |
| ▸ | CA6 | P23280 | 10/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 10/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 10/20 | 0.33 |
| ▸ | CA5A | P35218 | 8/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526602 | 0.77 | CA2 (0.50) | PTGES2CA12CA1CA2CA9 | |
| SCHEMBL6026242 | 0.77 | PTGES2 (0.35) | PTGES2CA12CA1CA2CA4 | |
| SCHEMBL6025521 | 0.74 | KMT2A (0.42) | CA2CA9 | |
| SCHEMBL6532201 | 0.71 | POLB (0.42) | CA1CA2 | |
| SCHEMBL6025780 | 0.70 | PTGES2 (0.39) | PTGES2CA12CA1CA2CA4 | |
| SCHEMBL6530536 | 0.70 | CA2 (0.38) | PTGES2CA12CA1CA2CA9 | |
| SCHEMBL6026291 | 0.68 | KMT2A (0.41) | CA2CA9 | |
| SCHEMBL6531288 | 0.68 | MEN1 (0.40) | CA2CA9 | |
| SCHEMBL6470757 | 0.63 | PKM (0.44) | — | |
| SCHEMBL6025635 | 0.63 | TAS2R14 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685119-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049594-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |