Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.48 |
| ▸ | SPPL2A | Q8TCT8 | 5/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.48 |
| ▸ | CTSD | P07339 | 3/20 | 0.46 |
| ▸ | CTSE | P14091 | 1/20 | 0.46 |
| ▸ | PGC | P20142 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11988962 | 0.88 | SPPL2A (0.53) | BACE1PSEN1PSEN2SPPL2AAPH1B | |
| SCHEMBL6477686 | 0.83 | CTSD (0.51) | CTSDCTSEPGCMLNRABCB11 | |
| SCHEMBL2584515 | 0.81 | BACE1 (0.51) | BACE1PSEN1PSEN2SPPL2AAPH1B | |
| SCHEMBL4875375 | 0.77 | CTSD (0.52) | BACE1CTSDMLNRABCB11LMNA | |
| SCHEMBL4875377 | 0.77 | CTSD (0.52) | BACE1CTSDMLNRABCB11LMNA | |
| SCHEMBL4872912 | 0.77 | MLNR (0.44) | SPPL2ACTSDMLNRABCB11LMNA | |
| SCHEMBL4872903 | 0.77 | MLNR (0.44) | SPPL2ACTSDMLNRABCB11LMNA | |
| SCHEMBL7430780 | 0.77 | MLNR (0.44) | SPPL2ACTSDMLNRABCB11LMNA | |
| SCHEMBL7430773 | 0.77 | MLNR (0.44) | SPPL2ACTSDMLNRABCB11LMNA | |
| SCHEMBL11989439 | 0.76 | SPPL2A (0.48) | BACE1PSEN1PSEN2SPPL2AAPH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3657002-B2 | — | — | 2005-06-08 | — | — | JP | claimed |
| WO-1994004492-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | claimed |