Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.32 |
| ▸ | LIPC | P11150 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320087 | 0.80 | KCNH2 (0.50) | KCNH2CYP3A4POLBKDM4EPRKD3 | |
| SCHEMBL5725020 | 0.75 | KCNH2 (0.44) | KCNH2CYP3A4POLBKDM4EPRKD3 | |
| SCHEMBL4370115 | 0.74 | KCNH2 (0.41) | KCNH2CYP3A4POLBKDM4EPRKD3 | |
| SCHEMBL4371545 | 0.71 | KCNH2 (0.43) | KCNH2CYP3A4KDM4E | |
| SCHEMBL6489214 | 0.71 | KCNH2 (0.74) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL6377878 | 0.69 | KCNH2 (0.75) | KCNH2CYP3A4POLBKDM4EPRKD3 | |
| SCHEMBL9867308 | 0.68 | PIM1 (0.45) | KCNH2CYP3A4POLBPRKD3ALDH1A1 | |
| SCHEMBL8540093 | 0.67 | KCNH2 (0.41) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL140764 | 0.67 | KCNH2 (0.37) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL6378744 | 0.67 | KCNH2 (0.44) | KCNH2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005026165-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | claimed |