Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527189 | 0.80 | KCNH2 (0.50) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5725020 | 0.79 | KCNH2 (0.44) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4370115 | 0.78 | KCNH2 (0.41) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16011744 | 0.77 | KCNH2 (0.55) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5320083 | 0.76 | KDM4E (0.60) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5569300 | 0.74 | KDM4E (0.50) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8992827 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL8540093 | 0.72 | KCNH2 (0.41) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4371545 | 0.72 | KCNH2 (0.43) | KCNH2KDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL8074220 | 0.71 | KDM4E (0.66) | KCNH2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099431-A2 | AN AQUEOUS LIQUID PHARMACEUTICAL COMPOSITIONS OF GATIFLOXACIN | WOCKHARDT LTD (IN) | 2007-09-07 | — | — | WO | disclosed |