Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 11/20 | 0.36 |
| ▸ | TOP1 | P11387 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3726196 | 0.79 | ALDH1A1 (0.40) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| Hydrochloric Acid SCHEMBL10432289 | 0.78 | PIM3 (0.49) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL5725020 | 0.71 | KCNH2 (0.44) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL5320087 | 0.70 | KCNH2 (0.50) | PRKD3ALDH1A1POLBOPRM1KCNH2 | |
| SCHEMBL8992827 | 0.69 | ALDH1A1 (0.42) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9149995 | 0.69 | ALDH1A1 (0.62) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL6527189 | 0.68 | KCNH2 (0.50) | PRKD3ALDH1A1POLBOPRM1KCNH2 | |
| SCHEMBL9660053 | 0.67 | ALDH1A1 (0.74) | PRKD3ALDH1A1POLBCHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL6005743 | 0.66 | ALDH1A1 (0.48) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL13963481 | 0.65 | ALDH1A1 (0.68) | ALDH1A1POLBCHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047538-A | Quinolinecarboxylic acid antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1991-09-10 | — | — | US | disclosed |