Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | RXRB | P28702 | 4/20 | 0.64 |
| ▸ | RXRA | P19793 | 3/20 | 0.64 |
| ▸ | RXRG | P48443 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729878 | 0.97 | TSHR (0.93) | TSHRALOX15HSD17B10RXRBRXRA | |
| SCHEMBL12151250 | 0.85 | ALOX15 (0.74) | TSHRALOX15HSD17B10RXRBRXRA | |
| SCHEMBL2729594 | 0.81 | TSHR (0.69) | TSHRALOX15HSD17B10RXRBRXRA | |
| SCHEMBL7520647 | 0.81 | ALOX15 (0.68) | TSHRALOX15HSD17B10MAPTL3MBTL1 | |
| SCHEMBL7320294 | 0.80 | TSHR (0.67) | TSHRALOX15HSD17B10RXRBRXRA | |
| SCHEMBL23321027 | 0.80 | ALOX15 (0.66) | TSHRALOX15HSD17B10PTPN7HRH3 | |
| SCHEMBL6295777 | 0.80 | HSD17B10 (0.66) | TSHRALOX15HSD17B10RXRBRXRA | |
| SCHEMBL31396966 | 0.80 | TSHR (0.66) | TSHRALOX15HSD17B10RXRBRXRA | |
| SCHEMBL11472768 | 0.80 | TSHR (0.66) | TSHRALOX15HSD17B10RXRBRXRA | |
| SCHEMBL7527304 | 0.80 | HSD17B10 (0.66) | TSHRALOX15HSD17B10RXRBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210200088-A1 | RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2021-07-01 | — | — | US | disclosed |
| US-20210200087-A1 | RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2021-07-01 | — | — | US | disclosed |
| US-20210200086-A1 | RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2021-07-01 | — | — | US | disclosed |
| US-20210093619-A1 | Chemical Compounds as ATF-4 Pathway Inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-04-01 | — | — | US | disclosed |
| WO-2005122766-A1 | FUNGICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093619-A1 | Chemical Compounds as ATF-4 Pathway Inhibitors | ATF4, ATF1, XBP1 | TSHR 3475/4885ALOX15 2546/4885HSD17B10 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.