Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956956 | 0.71 | AURKA (0.50) | HTR2C | |
| SCHEMBL103894 | 0.70 | HTR2C (0.53) | HTR2CL3MBTL1ADORA2ANUDT1 | |
| SCHEMBL5486787 | 0.69 | EPHB4 (0.45) | HTR2CL3MBTL1ADORA2ADYRK1A | |
| SCHEMBL5488996 | 0.69 | HTR2C (0.40) | HTR2CL3MBTL1ADORA2ADYRK1ANUDT1 | |
| SCHEMBL5489000 | 0.68 | EPHB4 (0.53) | — | |
| SCHEMBL5481710 | 0.68 | HTR2C (0.48) | HTR2CL3MBTL1ADORA2ADYRK1ANUDT1 | |
| SCHEMBL24386932 | 0.67 | HTR2C (0.50) | HTR2CL3MBTL1NUDT1 | |
| SCHEMBL9970925 | 0.67 | HTR2C (0.50) | HTR2CL3MBTL1NUDT1 | |
| SCHEMBL19865160 | 0.67 | L3MBTL1 (0.53) | HTR2CL3MBTL1ADORA2ANUDT1 | |
| SCHEMBL5477688 | 0.67 | NUDT1 (0.55) | HTR2CL3MBTL1ADORA2ADYRK1ANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019220-A2 | SUBSTITUTED IMIDAZO[1,2-A]PYRAZINES AS MODULATORS OF KINASE ACTIVITY | CELLULAR GENOMICS INC. (US) | 2005-03-03 | — | — | WO | disclosed |