Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335153 | 0.79 | AKR1B1 (0.59) | KDM4ELMNAPOLBAKR1B1 | |
| SCHEMBL6527987 | 0.76 | ENPP1 (0.47) | MEN1KMT2ATP53RAB9ANPC1 | |
| SCHEMBL12243297 | 0.76 | PLA2G4B (0.52) | TP53ALPLRAB9ANPC1ALDH1A1 | |
| SCHEMBL6628100 | 0.76 | ADRB1 (0.42) | RAB9ANPC1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL6492917 | 0.75 | ADRB1 (0.39) | MEN1TP53POLBTHRBTDP1 | |
| SCHEMBL19626581 | 0.75 | ENPP3 (0.66) | MEN1KMT2ATP53RAB9ANPC1 | |
| SCHEMBL6488755 | 0.75 | ENPP3 (0.50) | MEN1KMT2ATP53RAB9ANPC1 | |
| SCHEMBL23135332 | 0.74 | SMN1; SMN2 (0.58) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6647862 | 0.74 | ENPP3 (0.52) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL15711821 | 0.74 | ENPP3 (0.46) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864268-B2 | β3 adrenergic receptor agonists | PFIZER INC. (US) | 2005-03-08 | — | — | US | disclosed |