Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 6/20 | 0.66 |
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326200 | 0.83 | ENPP3 (0.60) | ENPP3TP53POLBTHRBTDP1 | |
| SCHEMBL27988175 | 0.82 | TP53 (0.48) | ENPP3TP53POLBTHRBTDP1 | |
| SCHEMBL201523 | 0.81 | ENPP3 (0.96) | ENPP3TP53POLBTHRBTDP1 | |
| SCHEMBL19625391 | 0.80 | TP53 (0.46) | ENPP3TP53POLBTHRBTDP1 | |
| SCHEMBL12112408 | 0.76 | ENPP3 (0.96) | ENPP3TP53POLBTHRBENPP1 | |
| SCHEMBL2056108 | 0.75 | TP53 (0.69) | ENPP3TP53POLBTHRBTDP1 | |
| SCHEMBL6527993 | 0.75 | MEN1 (0.50) | ENPP3TP53POLBTHRBTDP1 | |
| Ammonia Solution, Strong SCHEMBL28862464 | 0.74 | ENPP3 (0.92) | ENPP3TP53POLBTHRBTDP1 | |
| SCHEMBL6996945 | 0.73 | ENPP3 (0.60) | ENPP3TP53POLBTHRBTDP1 | |
| SCHEMBL12243297 | 0.73 | PLA2G4B (0.52) | ENPP3TP53ENPP1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | WNT1, WNT3A, CTNNB1 | ENPP3 570/4885TP53 2830/4885POLB 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.