Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | TK2 | O00142 | 1/20 | 0.30 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282272 | 0.90 | BCHE (0.32) | BCHE | |
| SCHEMBL14217397 | 0.87 | TK1 (0.33) | TK2TK1 | |
| SCHEMBL12373094 | 0.85 | TOP2A (0.36) | BCHE | |
| SCHEMBL2276807 | 0.85 | LMNA (0.34) | TK2TK1 | |
| SCHEMBL2283594 | 0.84 | TK1 (0.39) | TK1 | |
| SCHEMBL2281293 | 0.80 | POLB (0.41) | TK1 | |
| SCHEMBL12373098 | 0.79 | — | — | |
| SCHEMBL2284831 | 0.76 | TOP2A (0.39) | BCHE | |
| SCHEMBL2284827 | 0.76 | TOP2A (0.39) | BCHE | |
| SCHEMBL12373120 | 0.75 | TK1 (0.39) | TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063787-A2 | PROPARGYL SUBSTITUTED NUCLEOSIDE COMPOUNDS AND METHODS | APPLERA CORPORATION (US) | 2005-07-14 | — | — | WO | disclosed |