Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202432 | 0.86 | IDO1 (0.43) | HTR1BTAAR1IDO1AGXTFGFR1 | |
| SCHEMBL6530140 | 0.82 | ALDH1A1 (0.46) | TAAR1IDO1AGXTSIGMAR1MAOB | |
| SCHEMBL6528671 | 0.78 | PNMT (0.40) | TAAR1IDO1AGXTCDC7DBF4 | |
| SCHEMBL11206445 | 0.77 | CHRM2 (0.44) | TAAR1IDO1AGXTSIGMAR1CHRM2 | |
| SCHEMBL1196870 | 0.77 | MAOB (0.40) | TAAR1MAOBHRH3CDC7DBF4 | |
| SCHEMBL2103486 | 0.75 | FGFR1 (0.50) | HTR1BTAAR1IDO1AGXTFGFR1 | |
| SCHEMBL224560 | 0.74 | TAAR1 (0.51) | TAAR1SIGMAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL248658 | 0.73 | CHRM2 (0.57) | TAAR1IDO1AGXTSIGMAR1MAOB | |
| SCHEMBL6529172 | 0.71 | IDO1 (0.39) | TAAR1IDO1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL8305017 | 0.71 | TAAR1 (0.58) | TAAR1IDO1AGXTSIGMAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |