Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528363 | 0.85 | MAPT (0.38) | NOTUMCYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL6506652 | 0.80 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1GAAMEN1 | |
| SCHEMBL6528870 | 0.79 | NOTUM (0.39) | NOTUMCYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL6529673 | 0.79 | ALDH1A1 (0.49) | CYP4F2CYP4A11ALDH1A1GAAMEN1 | |
| SCHEMBL6510219 | 0.78 | CYP4F2 (0.46) | CYP4F2CYP4A11ALDH1A1GAAMEN1 | |
| SCHEMBL6508554 | 0.73 | ALDH1A1 (0.43) | CYP4F2CYP4A11ALDH1A1GAAMEN1 | |
| SCHEMBL22248030 | 0.72 | NOTUM (0.66) | NOTUMALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5660336 | 0.69 | NOTUM (0.61) | NOTUMALDH1A1GAAMEN1KMT2A | |
| SCHEMBL5940440 | 0.69 | NOTUM (0.62) | NOTUMCYP4F2CYP4A11ALDH1A1MEN1 | |
| SCHEMBL6718325 | 0.68 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100318-A1 | ALKANOIC ACIDS AND THEIR ESTERS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2005-10-27 | — | — | WO | claimed |
| WO-2005100318-A1 | ALKANOIC ACIDS AND THEIR ESTERS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2005-10-27 | — | — | WO | disclosed |