Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528744 | 0.88 | THRB (0.36) | ALDH1A1GAAKMT2AMAPTCYP4F2 | |
| SCHEMBL6509824 | 0.83 | CYP4F2 (0.34) | ALDH1A1GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL6530940 | 0.83 | KMT2A (0.39) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL6527238 | 0.81 | NPSR1 (0.45) | ALDH1A1GAAL3MBTL1MAPTCYP4F2 | |
| SCHEMBL6528531 | 0.79 | NOTUM (0.46) | NOTUMALDH1A1GAAMEN1KMT2A | |
| SCHEMBL6502389 | 0.77 | ALDH1A1 (0.38) | ALDH1A1GAAKMT2ACYP4F2CYP4A11 | |
| SCHEMBL6528869 | 0.72 | PPARG (0.46) | — | |
| SCHEMBL6528363 | 0.66 | MAPT (0.38) | NOTUMALDH1A1GAAKMT2AL3MBTL1 | |
| SCHEMBL22248030 | 0.65 | NOTUM (0.66) | NOTUMALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6530164 | 0.63 | PPARG (0.34) | ALDH1A1KMT2AMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056536-A1 | ANTIDIABETIC AGENTS WHICH EXHIBIT ACTIVITY AGAINST PPAR | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-23 | — | — | WO | disclosed |