Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16701357 | 0.91 | KDM4E (0.33) | KDM4EPOLBTDP1 | |
| SCHEMBL11873651 | 0.83 | KDM4E (0.31) | KDM4EPOLBTDP1 | |
| SCHEMBL27783120 | 0.81 | RAB9A (0.44) | KDM4EPOLBTDP1MEN1KMT2A | |
| SCHEMBL11833468 | 0.77 | KDM4E (0.35) | KDM4EPOLBTDP1MEN1KMT2A | |
| SCHEMBL2489037 | 0.75 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11031928 | 0.75 | KDM4E (0.39) | KDM4EPOLBTDP1MEN1KMT2A | |
| SCHEMBL973944 | 0.75 | KDM4E (0.39) | KDM4EPOLBTDP1MEN1KMT2A | |
| SCHEMBL8652753 | 0.75 | KDM4E (0.39) | KDM4EPOLBTDP1MEN1KMT2A | |
| SCHEMBL7239582 | 0.73 | — | — | |
| SCHEMBL6431047 | 0.72 | KDM4E (0.38) | KDM4EPOLBTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104987330-A | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH | 2015-10-21 | — | — | CN | claimed |
| CN-103492380-A | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH | 2014-01-01 | — | — | CN | claimed |
| CN-102414175-A | Insecticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2012-04-11 | — | — | CN | claimed |
| CN-101663289-A | Piperazinyl-propyl-pyrazole derivatives and the pharmaceutical composition that comprises them as dopamine d 4 receptor antagonists | KOREA RES INST CHEM TECH | 2010-03-03 | — | — | CN | claimed |
| CN-100400519-C | N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines | FMC CORP (DE) | 2008-07-09 | — | — | CN | claimed |
| CN-101139340-A | N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines | BAYER CROPSCIENCE AG (US) | 2008-03-12 | — | — | CN | claimed |
| CN-1729178-A | N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines | FMC CORP (US) | 2006-02-01 | — | — | CN | claimed |
| CN-1196692-C | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2005-04-13 | — | — | CN | claimed |
| CN-1105106-C | Naphthol derivatives and process for preparation thereof | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-04-09 | — | — | CN | claimed |
| CN-1317004-A | Benzoyl derivatives, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-10 | — | — | CN | claimed |
| CN-1208439-A | Process for the preparation of substituted aryl lactic acid containing cyclodepsipeptides with 24 ring atoms | BAYER AG (DE) | 1999-02-17 | — | — | CN | claimed |
| CN-1157619-A | Pyrimido [5-4-d] pyrimidines, drugs containing these compounds, their use and process for preparing them | THOMAE GMBH DR K (DE) | 1997-08-20 | — | — | CN | claimed |
| CN-1046898-A | 1-Aryimidazole insecticides | RHONE POULENC AGROCHIMIE (FR) | 1990-11-14 | — | — | CN | claimed |
| CN-87103552-A | Adopt malonate derivative to improve crop yield | — | 1988-07-06 | — | — | CN | claimed |
| CN-104987330-A | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH | 2015-10-21 | — | — | CN | disclosed |
| CN-102596933-B | Herbicidal pyrimidone derivatives | DU PONT | 2014-09-17 | — | — | CN | disclosed |
| CN-101663289-B | Piperazinyl-propyl-pyrazole derivatives as dopamine d4 receptor antagonists, and pharmaceutical compositions containing the same | KOREA RES INST CHEM TECH | 2014-07-23 | — | — | CN | disclosed |
| EP-0286346-A2 | Insecticidal substituted indazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-12 | — | — | EP | disclosed |
| CN-87103552-A | Adopt malonate derivative to improve crop yield | — | 1988-07-06 | — | — | CN | disclosed |
| CN-85105723-A | Herbicidal compositions containing 1-aryl-4-substituted-1, 4-dihydro-5H-tetrazol-5-ones and their sulfur analogs | — | 1986-05-10 | — | — | CN | disclosed |