Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528896 | 0.91 | KDM4E (0.36) | KDM4EPOLBTDP1 | |
| SCHEMBL11873651 | 0.75 | KDM4E (0.31) | KDM4EPOLBTDP1 | |
| SCHEMBL27783120 | 0.74 | RAB9A (0.44) | KDM4EPOLBTDP1 | |
| SCHEMBL7239582 | 0.71 | — | — | |
| SCHEMBL11833468 | 0.70 | KDM4E (0.35) | KDM4EPOLBTDP1 | |
| SCHEMBL1079249 | 0.69 | CA2 (0.40) | KDM4EPOLBTDP1 | |
| SCHEMBL2489037 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL11031928 | 0.68 | KDM4E (0.39) | KDM4EPOLBTDP1 | |
| SCHEMBL8652753 | 0.68 | KDM4E (0.39) | KDM4EPOLBTDP1 | |
| SCHEMBL973944 | 0.68 | KDM4E (0.39) | KDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066085-A1 | PROCESS FOR THE SYNTHESIS OF AN INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR | Incyte Holdings Corporation (US) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015070007-A1 | PROCESS FOR THE SYNTHESIS OF AN INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR | INCYTE CORPORATION (US) | 2015-05-14 | — | — | WO | disclosed |