Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4507891 | 1.00 | P2RX7 (0.56) | P2RX7LMNASMN1; SMN2PTGER4GAA | |
| SCHEMBL13958658 | 0.90 | P2RX7 (0.55) | P2RX7LMNASMN1; SMN2GAACYP2C19 | |
| SCHEMBL13958670 | 0.90 | P2RX7 (0.55) | P2RX7LMNASMN1; SMN2GAACYP2C19 | |
| Hydrochloric Acid SCHEMBL4500468 | 0.90 | P2RX7 (0.54) | P2RX7LMNASMN1; SMN2GAACYP2C19 | |
| SCHEMBL4507550 | 0.90 | P2RX7 (0.54) | P2RX7LMNASMN1; SMN2GAACYP2C19 | |
| Hydrochloric Acid SCHEMBL4509750 | 0.90 | P2RX7 (0.54) | P2RX7LMNASMN1; SMN2GAACYP2C19 | |
| SCHEMBL13958661 | 0.90 | P2RX7 (0.54) | P2RX7LMNASMN1; SMN2GAACYP2C19 | |
| Hydrochloric Acid SCHEMBL4507880 | 0.90 | P2RX7 (0.54) | P2RX7LMNASMN1; SMN2GAACYP2C19 | |
| Hydrochloric Acid SCHEMBL4508098 | 0.89 | P2RX7 (0.53) | P2RX7LMNASMN1; SMN2GAACYP2C19 | |
| SCHEMBL4508248 | 0.88 | P2RX7 (0.56) | P2RX7LMNASMN1; SMN2GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090524-A1 | Novel adamantane derivatives | ASTRAZENECA AB (SE) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090524-A1 | Novel adamantane derivatives | ADRA1A, ADORA1, ADRA1D | P2RX7 732/4885LMNA 1999/4885SMN1; SMN2 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.