Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529244 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL1075720 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL693498 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL693077 | 0.71 | GRK6 (0.36) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL3781653 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL678091 | 0.66 | GABRP (0.46) | — | |
| SCHEMBL7089484 | 0.65 | GABRP (0.47) | — | |
| SCHEMBL3777245 | 0.64 | ALDH1A1 (0.33) | KDM4EALDH1A1GLAPOLBGAA | |
| SCHEMBL1074632 | 0.63 | KDR (0.33) | ALDH1A1 | |
| SCHEMBL5282197 | 0.63 | SLC9A1 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881848-B2 | Process for preparing 4-trifluoromethylsulfinylpyrazole derivative | BASF Agro B.V. Arnhem (NL), Wädenswil-Branch (CH) | 2005-04-19 | — | — | US | disclosed |
| EP-1222173-B1 | PROCESS FOR PREPARING 4-TRIFLUOROMETHYLSULPHINYLPYRAZOLE DERIVATIVE | BAYER CROPSCIENCE SA (FR) | 2004-08-18 | — | — | EP | disclosed |
| US-20040034234-A1 | Process for preparing 4-trifluoromethylsulfinylpyrazole derivative | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 2004-02-19 | — | — | US | disclosed |
| US-6620943-B1 | Oxidation of 5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl) -3-cyano-4-trifluoromethylthiopyrazole with trifluoroperacetic acid in the presence of boric acid to form fipronil, used as pesticides | BAYER CROPSCIENCE SA (FR) | 2003-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034234-A1 | Process for preparing 4-trifluoromethylsulfinylpyrazole derivative | CYP2F1, CYP4F2, F12 | KDM4E 3990/4885ALDH1A1 346/4885GLA 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.