Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.41 |
| ▸ | CCKAR | P32238 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065542 | 0.79 | CCKBR (0.51) | CCKBRCCKAR | |
| SCHEMBL644107 | 0.79 | CCKBR (0.56) | CCKBRCCKARMEN1KMT2AALDH1A1 | |
| SCHEMBL642941 | 0.71 | CCKBR (0.59) | CCKBRCCKAR | |
| SCHEMBL642940 | 0.71 | CCKBR (0.59) | CCKBRCCKAR | |
| SCHEMBL644101 | 0.68 | CCKBR (0.70) | CCKBRCCKAR | |
| SCHEMBL643979 | 0.64 | CCKBR (0.64) | CCKBRCCKAR | |
| SCHEMBL9526481 | 0.64 | CCKBR (0.59) | CCKBRCCKARMEN1KMT2AALDH1A1 | |
| Nitrazepate SCHEMBL11833501 | 0.63 | LMNA (0.58) | CCKBRMEN1KMT2AALDH1A1LMNA | |
| Nitrazepate SCHEMBL29588849 | 0.63 | LMNA (0.58) | CCKBRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11825099 | 0.63 | LMNA (0.51) | CCKBRMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090319-A1 | PROCESS FOR PREPARING BENZODIAZEPINES | ARROW THERAPEUTICS LIMITED (GB) | 2005-09-29 | — | — | WO | claimed |