SCHEMBL6529431

SCHEMBL6529431

Sc1nc(-c2ncccn2)ns1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 1/20 0.30
COPS5 Q92905 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9852110 0.73 ADORA2A (0.55)
SCHEMBL6529561 0.70 NPC1 (0.36)
SCHEMBL171853 0.67 HDAC8 (0.47)
SCHEMBL6529837 0.66 POLB (0.50)
SCHEMBL22761405 0.65 KDM4E (0.48)
SCHEMBL6530965 0.65 CCR1 (0.52)
Hydrochloric Acid SCHEMBL6534749 0.64 HDAC8 (0.44)
Hydrochloric Acid SCHEMBL6535289 0.64 HDAC8 (0.44)
SCHEMBL30800591 0.64 HDAC8 (0.44)
Iodide SCHEMBL28731796 0.64 HDAC8 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005068420-A1 UREA AND THIOUREA COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2005-07-28 WO claimed
WO-2005026139-A1 NEMATICIDAL DIFLUOROALKENES BAYER CROPSCIENCE AG (DE) 2005-03-24 WO disclosed