SCHEMBL6530965

SCHEMBL6530965

Cc1cccc(-c2nsc(S)n2)n1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.52
CCR8 P51685 1/20 0.52
CYP2A6 P11509 1/20 0.39
METAP2 P50579 1/20 0.39
TGFBR1 P36897 11/20 0.37
NOS3 P29474 1/20 0.35
NOS2 P35228 1/20 0.35
IDH1 O75874 1/20 0.35
MAPK14 Q16539 2/20 0.34
GRM5 P41594 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
TGFBR2 P37173 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6528121 0.75 NOS3 (0.35) NOS3NOS2
SCHEMBL4167622 0.72 CCR1 (0.71) CCR1CCR8CYP2A6METAP2TGFBR1
SCHEMBL8802953 0.71 CYP19A1 (0.31)
SCHEMBL29388304 0.71 CCR1 (1.00) CCR1CCR8CYP2A6METAP2TGFBR1
SCHEMBL196966 0.71 CCR1 (1.00) CCR1CCR8CYP2A6METAP2TGFBR1
SCHEMBL30511194 0.71 CCR1 (1.00) CCR1CCR8CYP2A6METAP2TGFBR1
SCHEMBL23042515 0.70 RAB9A (0.50) METAP2
SCHEMBL9869261 0.69 L3MBTL1 (0.43)
SCHEMBL20557390 0.69 CCR1 (0.94) CCR1CCR8CYP2A6METAP2TGFBR1
SCHEMBL29751933 0.69 CCR1 (0.94) CCR1CCR8CYP2A6METAP2TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005026139-A1 NEMATICIDAL DIFLUOROALKENES BAYER CROPSCIENCE AG (DE) 2005-03-24 WO disclosed