Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932234 | 0.77 | KMT2A (0.49) | MAPTNPSR1L3MBTL1KMT2AHDAC1 | |
| SCHEMBL3382600 | 0.76 | PKM (0.57) | PKMNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8932271 | 0.73 | KMT2A (0.39) | KMT2AHDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL9005068 | 0.72 | CYP11B1 (0.38) | RAB9AMAPTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL8932257 | 0.72 | SMN1; SMN2 (0.34) | PKMNPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL8932244 | 0.71 | KMT2A (0.48) | PKMNPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL8932307 | 0.71 | MEN1 (0.34) | PKMNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9005032 | 0.70 | RAB9A (0.42) | NPC1RAB9AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9004994 | 0.70 | HDAC1 (0.39) | MAPTL3MBTL1MEN1KMT2AHDAC1 | |
| SCHEMBL8932259 | 0.69 | PTGS1 (0.32) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | claimed |