Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533265 | 0.82 | PTAFR (0.46) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6532221 | 0.82 | MTNR1A (0.35) | P2RX4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6511729 | 0.81 | MEN1 (0.39) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6529609 | 0.76 | KMT2A (0.43) | LMNAKMT2AALDH1A1HPGDTSHR | |
| SCHEMBL6002543 | 0.72 | PPARA (0.53) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6505495 | 0.70 | ALDH1A1 (0.46) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6509090 | 0.70 | PTGER4 (0.44) | LMNAALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL30633029 | 0.69 | P2RX4 (0.41) | P2RX4ALDH1A1CYP2A6KDM4E | |
| SCHEMBL22129125 | 0.69 | P2RX4 (0.41) | P2RX4ALDH1A1CYP2A6KDM4E | |
| SCHEMBL4633656 | 0.69 | SLC1A3 (0.45) | P2RX4MEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |