Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529661 | 1.00 | HDAC1 (0.39) | HDAC1HDAC3HDAC2BCL2L1BAK1 | |
| SCHEMBL6513945 | 0.88 | HTT (0.40) | HDAC1HDAC3HDAC2BCL2L1BAK1 | |
| SCHEMBL6511182 | 0.85 | LMNA (0.39) | HDAC1HDAC3HDAC2BCL2L1BAK1 | |
| SCHEMBL6511178 | 0.85 | LMNA (0.39) | HDAC1HDAC3HDAC2BCL2L1BAK1 | |
| SCHEMBL6531028 | 0.81 | LMNA (0.36) | BCL2L1BAK1RORCHTTLMNA | |
| SCHEMBL6511915 | 0.79 | HTT (0.45) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6511912 | 0.79 | HTT (0.45) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6507843 | 0.79 | HDAC1 (0.54) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6507841 | 0.79 | HDAC1 (0.54) | HDAC1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL6508462 | 0.75 | MEP1B (0.47) | HDAC1HDAC3HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |