Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | OGA | O60502 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.43 |
| ▸ | HTR3B | O95264 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30770805 | 0.98 | ALOX5 (0.50) | ALOX5OGAHRH3HTR1AHTR2A | |
| SCHEMBL22547430 | 0.96 | ALOX5 (0.51) | ALOX5OGAHRH3HTR1AHTR2A | |
| SCHEMBL1275290 | 0.86 | HTR3A (0.62) | ALOX5OGAHRH3HTR1AHTR2A | |
| SCHEMBL3916764 | 0.86 | ALOX5 (0.52) | ALOX5OGAHRH3HTR1AHTR2A | |
| SCHEMBL13706046 | 0.84 | CYP2C19 (0.58) | ALOX5OGAHRH3HTR1AHTR2A | |
| SCHEMBL2412819 | 0.84 | HTR3E (0.58) | ALOX5OGAHRH3HTR1ADRD3 | |
| SCHEMBL3586961 | 0.84 | PHGDH (0.50) | ALOX5OGAHRH3HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL3849292 | 0.83 | HTR3E (0.57) | ALOX5OGAHRH3HTR1ADRD3 | |
| SCHEMBL14083328 | 0.82 | OGA (0.47) | ALOX5OGAHRH3HTR1AHTR2A | |
| SCHEMBL3826847 | 0.82 | HTR3E (0.60) | ALOX5OGAHRH3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725397-A | Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-06-24 | — | — | CN | disclosed |
| US-6916345-B2 | 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-07-12 | — | — | US | disclosed |