Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532387 | 1.00 | HTR6 (0.51) | HTR6KMT2AKDM4EALDH1A1THRB | |
| SCHEMBL6529706 | 1.00 | HTR6 (0.51) | HTR6KMT2AKDM4EALDH1A1THRB | |
| SCHEMBL7491511 | 0.93 | HTR6 (0.53) | HTR6KMT2AKDM4EALDH1A1THRB | |
| SCHEMBL6965309 | 0.87 | DYRK1A (0.45) | HTR6KDM4EALOX5ATM | |
| SCHEMBL7484514 | 0.83 | KMT2A (0.53) | HTR6KMT2AALDH1A1ATMPTGS2 | |
| SCHEMBL6965222 | 0.79 | HTR6 (0.36) | HTR6KMT2AKDM4EALDH1A1THRB | |
| SCHEMBL7482377 | 0.79 | HTR6 (0.48) | HTR6KMT2AMEN1 | |
| SCHEMBL7491819 | 0.79 | HTR6 (0.43) | HTR6KMT2APTGS2MEN1 | |
| SCHEMBL7479507 | 0.79 | KCNH2 (0.44) | HTR6KMT2AALOX5PTGS2MEN1 | |
| SCHEMBL6965218 | 0.79 | HTR6 (0.36) | HTR6KMT2AKDM4EALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | claimed |