Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965222 | 0.85 | HTR6 (0.36) | HTR6KDM4EATMRORCALOX5 | |
| SCHEMBL6965309 | 0.79 | DYRK1A (0.45) | HTR6KDM4EATMRORCALOX5 | |
| SCHEMBL6532387 | 0.79 | HTR6 (0.51) | HTR6KDM4EATMALOX5ALDH1A1 | |
| SCHEMBL6529706 | 0.79 | HTR6 (0.51) | HTR6KDM4EATMALOX5ALDH1A1 | |
| SCHEMBL6529704 | 0.79 | HTR6 (0.51) | HTR6KDM4EATMALOX5ALDH1A1 | |
| SCHEMBL6976183 | 0.77 | HTR6 (0.41) | HTR6KDM4EALOX5HTR1AHTR1D | |
| SCHEMBL6968081 | 0.77 | HTR6 (0.43) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL6968072 | 0.77 | HTR6 (0.43) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL6968579 | 0.77 | HTR6 (0.43) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL6976877 | 0.76 | HTR6 (0.61) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1289479-C | As 5-HT1D5-ring indole compounds of receptor ligands | ALLELIX BIOPHARMA (CA) | 2006-12-13 | — | — | CN | claimed |
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | claimed |
| CN-1245491-A | 5-cyclo indole compounds as 5-HT receptor ligands | ALLELIX BIOPHARMA (CA) | 2000-02-23 | — | — | CN | claimed |
| US-5998438-A | SEROTONIN RECEPTOR ANTAGONIST; HEADACHE THERAPY | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1999-12-07 | — | — | US | claimed |
| CN-1289479-C | As 5-HT1D5-ring indole compounds of receptor ligands | ALLELIX BIOPHARMA (CA) | 2006-12-13 | — | — | CN | disclosed |
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | disclosed |
| CN-1245491-A | 5-cyclo indole compounds as 5-HT receptor ligands | ALLELIX BIOPHARMA (CA) | 2000-02-23 | — | — | CN | disclosed |
| US-5998438-A | SEROTONIN RECEPTOR ANTAGONIST; HEADACHE THERAPY | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1999-12-07 | — | — | US | disclosed |
| EP-0944595-A1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | Allelix Biopharmaceuticals Inc. (CA) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023587-A1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1998-06-04 | — | — | WO | disclosed |