Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.60 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529971 | 0.84 | DPP4 (0.75) | DPP4DPP8DPP7 | |
| SCHEMBL6528894 | 0.80 | DPP4 (0.52) | DPP4DPP8DPP7CNR2CNR1 | |
| SCHEMBL6533454 | 0.76 | DPP4 (0.59) | DPP4DPP8DPP7VNN1 | |
| SCHEMBL24928349 | 0.71 | DPP4 (0.58) | DPP4DPP8DPP7CNR2ELANE | |
| SCHEMBL6530976 | 0.68 | ACKR3 (0.39) | DPP4DPP8DPP7GRM2ALDH1A1 | |
| SCHEMBL6530636 | 0.68 | DPP4 (0.74) | DPP4DPP8DPP7 | |
| SCHEMBL6531194 | 0.68 | DPP4 (0.69) | DPP4DPP8DPP7ALDH1A1L3MBTL1 | |
| SCHEMBL6527980 | 0.67 | DPP4 (0.45) | DPP4DPP8DPP7ALDH1A1L3MBTL1 | |
| SCHEMBL6531965 | 0.67 | DPP4 (0.82) | DPP4DPP8DPP7 | |
| SCHEMBL6531765 | 0.67 | DPP4 (1.00) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |