Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.59 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529969 | 0.76 | DPP4 (0.60) | DPP4DPP8DPP7VNN1 | |
| SCHEMBL6530262 | 0.69 | DPP4 (0.45) | DPP4DPP8DPP7 | |
| SCHEMBL6529971 | 0.65 | DPP4 (0.75) | DPP4DPP8DPP7 | |
| SCHEMBL6530127 | 0.64 | DPP4 (0.56) | DPP4DPP8DPP7POLB | |
| SCHEMBL6529684 | 0.64 | DPP4 (0.70) | DPP4DPP8DPP7 | |
| SCHEMBL9718295 | 0.58 | KDM4E (0.57) | DPP4 | |
| SCHEMBL6529810 | 0.58 | DPP4 (0.70) | DPP4DPP8DPP7 | |
| SCHEMBL6529422 | 0.57 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6532173 | 0.57 | DPP4 (0.83) | DPP4DPP8DPP7 | |
| SCHEMBL6530580 | 0.57 | DPP4 (0.82) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |