Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 12/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986727 | 1.00 | UGCG (0.47) | UGCGCYP3A4PSMB5ITGB1ITGA4 | |
| SCHEMBL13791833 | 0.92 | ECE1 (0.42) | UGCGCYP3A4PSMB5ITGB1ITGA4 | |
| SCHEMBL8298621 | 0.91 | PSMB5 (0.44) | UGCGCYP3A4PSMB5ITGB1ITGA4 | |
| SCHEMBL3992055 | 0.90 | P2RX7 (0.42) | UGCGCYP3A4PSMB5ITGB1ITGA4 | |
| SCHEMBL13986728 | 0.87 | PSMB5 (0.46) | PSMB5ITGB1ITGA4ECE1PTGER4 | |
| SCHEMBL4829787 | 0.86 | ITGB1 (0.51) | PSMB5ITGB1ITGA4ITGB7ECE1 | |
| SCHEMBL3989525 | 0.86 | ITGB1 (0.51) | PSMB5ITGB1ITGA4ITGB7ECE1 | |
| SCHEMBL6097133 | 0.86 | ITGB1 (0.51) | PSMB5ITGB1ITGA4ITGB7ECE1 | |
| SCHEMBL3991301 | 0.86 | ITGB1 (0.51) | PSMB5ITGB1ITGA4ITGB7ECE1 | |
| SCHEMBL4827806 | 0.85 | CDK2 (0.47) | PSMB5ITGB1ITGA4ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014534-A1 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | claimed |