Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506651 | 0.89 | S1PR1 (0.45) | S1PR1ATMGLASMN1; SMN2BACE1 | |
| SCHEMBL6529533 | 0.89 | S1PR1 (0.56) | S1PR1S1PR3PTPN1PTPN6PTPN11 | |
| SCHEMBL6532174 | 0.85 | PDE4A (0.45) | S1PR1S1PR3PTPN1PTPN6PTPN11 | |
| SCHEMBL6530516 | 0.84 | SLC13A5 (0.53) | S1PR1S1PR3 | |
| SCHEMBL6527585 | 0.83 | S1PR1 (0.39) | S1PR1S1PR3 | |
| SCHEMBL6500002 | 0.82 | S1PR1 (0.41) | S1PR1S1PR3 | |
| SCHEMBL6504731 | 0.82 | S1PR1 (0.47) | S1PR1ALDH1A1S1PR3MEN1MAPT | |
| SCHEMBL6529691 | 0.81 | SLC13A5 (0.43) | S1PR1S1PR3PTPN11 | |
| SCHEMBL6529754 | 0.80 | ESR1 (0.38) | S1PR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL6529144 | 0.79 | S1PR1 (0.45) | S1PR1S1PR3PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |