Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530897 | 0.86 | L3MBTL1 (0.60) | TP53MAPTL3MBTL1EGFROPRM1 | |
| SCHEMBL6512975 | 0.85 | TP53 (0.45) | TP53MAPTL3MBTL1EGFROPRM1 | |
| SCHEMBL6532288 | 0.80 | ACSL1 (0.41) | L3MBTL1EGFROPRM1OPRK1OGFRL1 | |
| SCHEMBL6530899 | 0.79 | OPRM1 (0.43) | TP53L3MBTL1EGFROPRM1OPRK1 | |
| SCHEMBL6528422 | 0.77 | L3MBTL1 (0.60) | TP53L3MBTL1OPRM1OPRK1OGFRL1 | |
| SCHEMBL6530018 | 0.73 | L3MBTL1 (0.55) | L3MBTL1OPRM1OPRK1OGFRL1HDAC6 | |
| SCHEMBL6528750 | 0.72 | L3MBTL1 (0.60) | TP53L3MBTL1EGFROPRM1OPRK1 | |
| SCHEMBL6529610 | 0.72 | L3MBTL1 (0.54) | L3MBTL1EGFROPRM1OPRK1OGFRL1 | |
| SCHEMBL6532045 | 0.71 | L3MBTL1 (0.58) | L3MBTL1OPRM1OPRK1OGFRL1HDAC6 | |
| SCHEMBL6530967 | 0.71 | L3MBTL1 (0.61) | TP53MAPTL3MBTL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019186-A1 | 2-AMINOBENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF HIV/AIDS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | disclosed |