Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20966396 | 0.92 | TSHR (0.53) | KDM4ENPC1RAB9ACYP3A4CYP2D6 | |
| SCHEMBL6528467 | 0.83 | L3MBTL1 (0.53) | KDM4EL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL28282944 | 0.81 | KDM4E (0.59) | KDM4EL3MBTL1NPC1RAB9AELANE | |
| SCHEMBL6527214 | 0.78 | MAPT (0.58) | KDM4EL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL20689339 | 0.77 | ELANE (0.48) | KDM4EL3MBTL1NPC1RAB9ACYP1A2 | |
| SCHEMBL11710830 | 0.77 | FGFR1 (0.46) | — | |
| SCHEMBL6528435 | 0.77 | KMT2A (0.51) | KDM4EL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL29504400 | 0.77 | KMT2A (0.51) | KDM4EL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL11263883 | 0.77 | ALDH1A1 (0.45) | KDM4ENPC1RAB9AHSD17B10ALDH1A1 | |
| SCHEMBL11235791 | 0.76 | CYP3A4 (0.48) | L3MBTL1NPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107750251-A | Isoxazolyl-substituted imidazopyridines | 塞尔森瑞科有限责任公司 | 2018-03-02 | — | — | CN | disclosed |
| WO-2005021547-A2 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD. (AU) | 2005-03-10 | — | — | WO | disclosed |