Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530293 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL6530208 | 0.84 | SYK (0.52) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL6529620 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL6528645 | 0.82 | TSHR (0.55) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL8132914 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL3831190 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL8116977 | 0.76 | TSHR (0.48) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL6530872 | 0.75 | MGLL (0.45) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL6530879 | 0.75 | MGLL (0.45) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 | |
| SCHEMBL6511478 | 0.73 | MGLL (0.47) | SMN1; SMN2TSHRNPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |