Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 3/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530208 | 0.88 | SYK (0.52) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL6530292 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL6530293 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL6529833 | 0.81 | NPC1 (0.59) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL8132914 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL3831190 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL8116977 | 0.79 | TSHR (0.48) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL6528111 | 0.76 | MGLL (0.49) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL6963286 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2NPC1ALDH1A1TP53MAPT | |
| SCHEMBL6191868 | 0.76 | NPC1 (0.57) | SMN1; SMN2NPC1ALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |
| WO-2005082876-A1 | C-5 SUBSTITUTED FURANONE DIPEPTIDE CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2005-09-09 | — | — | WO | disclosed |