Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FSHR | P23945 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530872 | 1.00 | MGLL (0.45) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6528111 | 0.87 | MGLL (0.49) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL5861471 | 0.85 | MGLL (0.49) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6529297 | 0.80 | TSHR (0.45) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL5862878 | 0.77 | MGLL (0.47) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6530293 | 0.75 | SMN1; SMN2 (0.47) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6530292 | 0.75 | SMN1; SMN2 (0.47) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6528645 | 0.74 | TSHR (0.55) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6511478 | 0.71 | MGLL (0.47) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6511479 | 0.71 | MGLL (0.47) | MGLLTSHRTP53MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082900-A2 | OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |