Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530466 | 0.90 | ELANE (0.42) | KCNQ3KCNQ2MEN1KMT2AKDM4E | |
| SCHEMBL2830669 | 0.79 | HDAC1 (0.47) | KCNQ3KCNQ2MEN1KMT2ALMNA | |
| SCHEMBL9680768 | 0.73 | MAPT (0.71) | SIRT2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6530465 | 0.72 | RAB9A (0.41) | KCNQ3KCNQ2MEN1KMT2AKDM4E | |
| SCHEMBL22453708 | 0.71 | MAPT (0.64) | SIRT2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL1315232 | 0.70 | KCNQ3 (0.51) | KCNQ3KCNQ2MEN1KMT2AKDM4E | |
| SCHEMBL14516644 | 0.69 | KCNQ3 (0.74) | KCNQ3KCNQ2PTPN1MEN1KMT2A | |
| SCHEMBL6525767 | 0.69 | LIPE (0.43) | NAMPT | |
| SCHEMBL22453321 | 0.69 | SIRT2 (0.56) | SIRT2MEN1KMT2AMAPT | |
| SCHEMBL4217099 | 0.69 | ABCG2 (0.46) | SIRT2KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495002-A1 | BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS | Astrazeneca AB (SE) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087057-A1 | BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2003-10-23 | — | — | WO | disclosed |