Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830669 | 0.81 | HDAC1 (0.47) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL6530466 | 0.76 | ELANE (0.42) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL6530468 | 0.72 | SIRT2 (0.47) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL8242651 | 0.72 | MDM4 (0.54) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL6525767 | 0.71 | LIPE (0.43) | HDAC1 | |
| SCHEMBL2832030 | 0.68 | NAMPT (0.49) | RAB9ANPC1MEN1KMT2AHDAC1 | |
| SCHEMBL504005 | 0.67 | L3MBTL1 (0.55) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14516644 | 0.67 | KCNQ3 (0.74) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL21000444 | 0.67 | GSK3B (0.41) | RAB9AMEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL27828435 | 0.67 | CCNC (0.45) | HDAC1ALDH1A1NPSR1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495002-A1 | BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS | Astrazeneca AB (SE) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087057-A1 | BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2003-10-23 | — | — | WO | disclosed |