Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528788 | 0.89 | CTSK (0.43) | CTSKCTSSCTSLKCNH3 | |
| SCHEMBL6531499 | 0.85 | PDPK1 (0.45) | CTSK | |
| SCHEMBL6530210 | 0.84 | NPC1 (0.45) | CTSK | |
| SCHEMBL6530634 | 0.83 | CTSK (0.45) | CTSKCTSSCTSLKCNH3 | |
| SCHEMBL6528746 | 0.82 | CTSK (0.44) | CTSKCTSSCTSLKCNH3 | |
| SCHEMBL6531457 | 0.82 | ATM (0.45) | CTSKCTSSCTSLKCNH3 | |
| SCHEMBL6532662 | 0.81 | CTSK (0.42) | CTSKCTSSCTSLKCNH3 | |
| SCHEMBL6508189 | 0.81 | KCNH3 (0.41) | CTSKKCNH3 | |
| SCHEMBL6528931 | 0.81 | KCNH3 (0.41) | CTSKKCNH3 | |
| SCHEMBL6508192 | 0.81 | KCNH3 (0.41) | CTSKKCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003103-A2 | 2, 4, 6-TRI-SUBSTITUTED 6-MEMBERED HETEROCYCLES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003103-A2 | 2, 4, 6-TRI-SUBSTITUTED 6-MEMBERED HETEROCYCLES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | disclosed |