Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21163171 | 0.83 | ALDH1A1 (0.65) | PKMALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6529896 | 0.83 | DPP4 (0.59) | ALDH1A1DPP4TSHRMEN1KMT2A | |
| SCHEMBL6530405 | 0.82 | DPP4 (0.60) | ALDH1A1DPP4TSHRMEN1KMT2A | |
| SCHEMBL6530105 | 0.82 | DPP4 (0.60) | ALDH1A1DPP4TSHRMEN1KMT2A | |
| SCHEMBL6532846 | 0.81 | ALDH1A1 (0.50) | ALDH1A1DPP4TSHRMEN1KMT2A | |
| SCHEMBL6530714 | 0.80 | PKM (0.57) | PKMALDH1A1DPP4MEN1KMT2A | |
| SCHEMBL6530305 | 0.79 | DPP4 (0.72) | PKMDPP4KMT2AL3MBTL1DPP8 | |
| SCHEMBL6530702 | 0.79 | HSD17B10 (0.46) | ALDH1A1DPP4L3MBTL1HSD17B10DPP8 | |
| SCHEMBL6530822 | 0.79 | DPP4 (0.51) | ALDH1A1DPP4TSHRMEN1KMT2A | |
| SCHEMBL6533469 | 0.79 | HSD17B10 (0.44) | ALDH1A1DPP4TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |