Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408778 | 0.88 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9408745 | 0.87 | NPC1 (0.54) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9408934 | 0.87 | NPC1 (0.47) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL8518613 | 0.86 | KDM4E (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL8518615 | 0.86 | KDM4E (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL11396584 | 0.85 | RAB9A (0.38) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL8809730 | 0.85 | NPC1 (0.50) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9408822 | 0.85 | RAB9A (0.52) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9408879 | 0.85 | NPC1 (0.52) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL8043991 | 0.85 | NPC1 (0.52) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354007-A | Process for preparing oxidatively-stable polymers | SCOTT GERALD | 1982-10-12 | — | — | US | claimed |
| EP-2379512-B1 | TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF | NOVARTIS AG (CH) | 2017-03-29 | — | — | EP | disclosed |
| EP-2652532-B1 | OPHTHALMIC LENSES MODIFIED WITH FUNCTIONAL GROUPS AND METHODS OF MAKING THEREOF | NOVARTIS AG (CH) | 2016-06-08 | — | — | EP | disclosed |
| US-8899745-B2 | Ophthalmic lenses modified with functional groups and methods of making thereof | NOVARTIS AG (CH) | 2014-12-02 | — | — | US | disclosed |
| WO-2005042509-A1 | 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS | ALLERGAN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| EP-0834304-B1 | Use of liposomogenic UV absorbers to protect hair | CIBA SC HOLDING AG (CH) | 2005-01-26 | — | — | EP | disclosed |
| EP-0815071-B1 | LIPOSOMOGENIC UV ABSORBERS | CIBA SC HOLDING AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| US-6017556-A | PROTECTING HUMAN HAIR FROM THE DAMAGING EFFECT OF ULTRAVIOLET RADIATION BY TREATING HUMAN HAIR WITH A LIPOSOMOGENIC ULTRAVIOLET RADIATION ABSORBER | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-01-25 | — | — | US | disclosed |
| US-6015575-A | TRIAZINE, BENZOTRIAZOLE, BENZOPHENONE AND AMINOBENZOIC ACID DERIVATIVES AS RADIATION ABSORBERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0834304-A2 | Liposomogenic UV absorbers | Ciba SC Holding AG (CH) | 1998-04-08 | — | — | EP | disclosed |