Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408952 | 0.94 | NPC1 (0.47) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL8043981 | 0.93 | NPC1 (0.50) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL9408778 | 0.89 | NPC1 (0.56) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL8406921 | 0.88 | NPC1 (0.46) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL9408745 | 0.88 | NPC1 (0.54) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL8056945 | 0.86 | TTR (0.44) | NPC1RAB9ATTRLMNASMN1; SMN2 | |
| SCHEMBL9408822 | 0.86 | RAB9A (0.52) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL9408879 | 0.86 | NPC1 (0.52) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL8055374 | 0.85 | TTR (0.44) | NPC1RAB9APOLBTTRLMNA | |
| SCHEMBL8061576 | 0.85 | LMNA (0.47) | RAB9ATTRLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826511-B1 | Heat sensitive recording material | OJI PAPER CO (JP) | 2000-05-24 | — | — | EP | claimed |
| EP-0826511-A1 | Heat sensitive recording material | Oji Paper Co., Ltd. (JP) | 1998-03-04 | — | — | EP | claimed |
| EP-0826511-B1 | Heat sensitive recording material | OJI PAPER CO (JP) | 2000-05-24 | — | — | EP | disclosed |
| EP-0826511-A1 | Heat sensitive recording material | Oji Paper Co., Ltd. (JP) | 1998-03-04 | — | — | EP | disclosed |