Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SETDB1 | Q15047 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408778 | 0.91 | NPC1 (0.56) | NPC1RAB9APOLBLMNASETDB1 | |
| SCHEMBL8809730 | 0.88 | NPC1 (0.50) | NPC1RAB9APOLBLMNASETDB1 | |
| SCHEMBL9408879 | 0.88 | NPC1 (0.52) | NPC1RAB9APOLBLMNASETDB1 | |
| SCHEMBL8043991 | 0.88 | NPC1 (0.52) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL9408822 | 0.88 | RAB9A (0.52) | NPC1RAB9APOLBLMNASETDB1 | |
| SCHEMBL9408799 | 0.87 | NPC1 (0.51) | NPC1RAB9APOLBLMNASETDB1 | |
| SCHEMBL6530775 | 0.87 | NPC1 (0.51) | NPC1RAB9APOLBLMNASETDB1 | |
| SCHEMBL9291314 | 0.87 | NPC1 (0.51) | NPC1RAB9APOLBLMNASETDB1 | |
| SCHEMBL9324363 | 0.87 | RAB9A (0.54) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL9291411 | 0.86 | NPC1 (0.50) | NPC1RAB9APOLBLMNASETDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006161-B1 | INK COMPOSITION PROVIDING IMAGE EXCELLENT IN LIGHT STABILITY | SEIKO EPSON CORP (JP) | 2007-05-30 | — | — | EP | disclosed |
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | disclosed |