Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | SCD | O00767 | 2/20 | 0.44 |
| ▸ | FSHR | P23945 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529297 | 0.95 | TSHR (0.45) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6528111 | 0.89 | MGLL (0.49) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL5862878 | 0.87 | MGLL (0.47) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6530879 | 0.85 | MGLL (0.45) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6530872 | 0.85 | MGLL (0.45) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6530208 | 0.75 | SYK (0.52) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL8132914 | 0.74 | SMN1; SMN2 (0.50) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL22808203 | 0.73 | TP53 (0.61) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL6532124 | 0.73 | NPC1 (0.60) | MGLLTSHRTP53MAPTNPC1 | |
| SCHEMBL3831190 | 0.73 | SMN1; SMN2 (0.55) | MGLLTSHRTP53MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176610-A1 | Indolone oxazolidinones and derivatives thereof | PHARMACIA & UPJOHN COMPANY | 2004-09-09 | — | — | US | claimed |
| US-7012088-B2 | Indolone oxazolidinones and derivatives thereof | PHARMACIA & UPJOHN COMPANY (US) | 2006-03-14 | — | — | US | disclosed |
| EP-1599470-A1 | ANTIBACTERIAL INDOLONE OXAZOLIDINONES, INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Pharmacia & Upjohn Company LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2005082900-A2 | OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |
| US-20040176610-A1 | Indolone oxazolidinones and derivatives thereof | PHARMACIA & UPJOHN COMPANY | 2004-09-09 | — | — | US | disclosed |
| WO-2004074282-A1 | ANTIBACTERIAL INDOLONE OXAZOLIDINONES, INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176610-A1 | Indolone oxazolidinones and derivatives thereof | OXA1L, IDO1, NDUFS7 | MGLL 2261/4885TSHR 3233/4885TP53 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.