Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905044 | 0.99 | HPGD (0.58) | HPGDTSHRBRD4TP53CHRM2 | |
| Hydrochloric Acid SCHEMBL28741368 | 0.97 | HPGD (0.57) | HPGDTSHRBRD4TP53CHRM2 | |
| SCHEMBL7402106 | 0.95 | HPGD (0.61) | HPGDTSHRBRD4TP53CHRM2 | |
| SCHEMBL10755797 | 0.89 | HPGD (0.65) | HPGDTSHRBRD4TP53CHRM2 | |
| SCHEMBL10762307 | 0.83 | HPGD (0.69) | HPGDTSHRBRD4TP53CHRM2 | |
| SCHEMBL13532862 | 0.83 | HPGD (0.69) | HPGDTSHRBRD4TP53CHRM2 | |
| SCHEMBL10940620 | 0.79 | HPGD (0.60) | HPGDTSHRBRD4TP53CHRM2 | |
| SCHEMBL15387818 | 0.79 | DRD2 (0.52) | HPGDTSHRBRD4CHRM2CHRM4 | |
| SCHEMBL14560487 | 0.77 | ADRA1D (0.56) | BRD4GRM2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11472575 | 0.76 | TSHR (0.69) | HPGDTSHRBRD4TP53CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439766-A2 | Process for the preparation of N-acyl-4-phenyl-pyrrolidin-2-ones having cerebroprotective activity | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-08-07 | — | — | EP | claimed |
| JP-5032622-A | — | — | None | — | — | JP | disclosed |
| US-20050032858-A1 | Novel heterocyclic compound and anti-inflamatory agent | NIPPON SODA CO., LTD. (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1435353-A1 | NOVEL HETEROCYCLIC COMPOUND AND ANTI-INFLAMMATORY AGENT | NIPPON SODA CO., LTD. (JP) | 2004-07-07 | — | — | EP | disclosed |
| US-5441973-A | Treating cerebral functional disorders; nootropic agents | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1995-08-15 | — | — | US | disclosed |
| US-5441973-A | Treating cerebral functional disorders; nootropic agents | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1995-08-15 | — | — | US | disclosed |
| JP-H0532622-A | PREPARATION OF N-ACYL-4-PHENYL-PYRROLIDIN-2-ONE HAVING CEREBROPROTECTIVE EFFECT | ARZNEIMITTELWERK DRESDEN GMBH | 1993-02-09 | — | — | JP | disclosed |
| EP-0439766-A2 | Process for the preparation of N-acyl-4-phenyl-pyrrolidin-2-ones having cerebroprotective activity | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-08-07 | — | — | EP | disclosed |
| EP-0439766-A2 | Process for the preparation of N-acyl-4-phenyl-pyrrolidin-2-ones having cerebroprotective activity | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032858-A1 | Novel heterocyclic compound and anti-inflamatory agent | TLR5, IRF3, IL4 | HPGD 440/4885TSHR 4257/4885BRD4 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.