Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.42 |
| ▸ | CA9 | Q16790 | 10/20 | 0.42 |
| ▸ | CA1 | P00915 | 8/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273818 | 0.80 | MAPT (0.44) | CA12CA9CA1POLBGAA | |
| SCHEMBL4245639 | 0.80 | CA12 (0.45) | CA12CA9CA1CNR1CA2 | |
| SCHEMBL4245643 | 0.77 | CA12 (0.43) | CA12CA9CA1POLBGAA | |
| SCHEMBL1273266 | 0.76 | MAPT (0.61) | CA12CA9CA1POLBGAA | |
| SCHEMBL6532488 | 0.74 | CA12 (0.46) | CA12CA9CA1POLBGAA | |
| SCHEMBL1273704 | 0.72 | ALDH1A1 (0.46) | CA12CA9CA1POLBGAA | |
| SCHEMBL4250971 | 0.72 | CNR1 (0.46) | GAAMAPTNPSR1CNR1RAB9A | |
| SCHEMBL1273828 | 0.71 | POLB (0.46) | CA12CA9POLBGAAMAPT | |
| SCHEMBL1274226 | 0.71 | MAPT (0.54) | CA12CA9CA1POLBGAA | |
| SCHEMBL1274203 | 0.70 | POLB (0.46) | POLBMAPTTAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056532-A1 | INDAZOLE DERIVATIVES WHICH INTERACT WITH THE G-PROTEIN COUPLED RECEPTOR FAMILY | BIOFOCUS DISCOVERY LIMITED (GB) | 2005-06-23 | — | — | WO | disclosed |