Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
| ▸ | BMP1 | P13497 | 6/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273828 | 0.92 | POLB (0.46) | ALDH1A1KDM4ETAS2R14PTGER4BMP1 | |
| SCHEMBL1274203 | 0.89 | POLB (0.46) | ALDH1A1KDM4ETAS2R14BMP1POLB | |
| SCHEMBL1273266 | 0.85 | MAPT (0.61) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL1274226 | 0.85 | MAPT (0.54) | ALDH1A1POLBGAAMAPTNPSR1 | |
| SCHEMBL1273674 | 0.85 | PTGER4 (0.46) | ALDH1A1KDM4ETAS2R14PTGER4BMP1 | |
| SCHEMBL6532488 | 0.85 | CA12 (0.46) | CNR2POLBGAAMAPTNPSR1 | |
| SCHEMBL1273703 | 0.82 | POLB (0.47) | ALDH1A1KDM4ETAS2R14POLBGAA | |
| SCHEMBL1273818 | 0.81 | MAPT (0.44) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL1274193 | 0.79 | ALDH1A1 (0.49) | ALDH1A1POLBMAPT | |
| SCHEMBL1273700 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110038850-A1 | G Protein-Coupled Receptor and Modulators Thereof For The Treatment of Gaba-Related Neurological Disorders Including Sleep-Related Disorders | ARENA PHARMACEUTICALS, INC. | 2011-02-17 | — | — | US | disclosed |
| WO-2005056532-A1 | INDAZOLE DERIVATIVES WHICH INTERACT WITH THE G-PROTEIN COUPLED RECEPTOR FAMILY | BIOFOCUS DISCOVERY LIMITED (GB) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110038850-A1 | G Protein-Coupled Receptor and Modulators Thereof For The Treatment of Gaba-Related Neurological Disorders Including Sleep-Related Disorders | BRS3, GPR3, GABRA3 | ALDH1A1 4548/4885KDM4E 1514/4885TAS2R14 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.