Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.39 |
| ▸ | PPARA | Q07869 | 13/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532377 | 0.93 | PPARG (0.39) | PPARGPPARALTA4HPPARDTSHR | |
| SCHEMBL6532684 | 0.93 | PPARG (0.38) | PPARGPPARALTA4HPPARDTSHR | |
| SCHEMBL6533825 | 0.93 | PPARG (0.37) | PPARGPPARALTA4HPPARDROCK2 | |
| SCHEMBL6533886 | 0.90 | PPARG (0.36) | PPARGPPARAPPARDL3MBTL1ROCK1 | |
| SCHEMBL6533235 | 0.87 | PPARG (0.39) | PPARGPPARAPPARDROCK2ROCK1 | |
| SCHEMBL6534118 | 0.87 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL6532718 | 0.86 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL6533744 | 0.86 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL6533257 | 0.86 | ROCK2 (0.34) | PPARGPPARAROCK2 | |
| SCHEMBL6532383 | 0.86 | PPARG (0.40) | PPARGPPARAROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |