Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470754 | 0.81 | CA2 (0.45) | CA12CA2CA1CA5A | |
| SCHEMBL6025032 | 0.78 | KMT2A (0.41) | LMNAMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL6025517 | 0.77 | KMT2A (0.44) | MEN1KMT2AALDH1A1THRBMAPT | |
| SCHEMBL6025286 | 0.74 | BCL2L1 (0.35) | MEN1KMT2ACA12MAPTCA2 | |
| SCHEMBL6532201 | 0.72 | POLB (0.42) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6468789 | 0.72 | KMT2A (0.52) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6025780 | 0.70 | PTGES2 (0.39) | ALDH1A1GAACA12CA2CA1 | |
| SCHEMBL6530534 | 0.70 | PTGES2 (0.39) | CA12CA2CA1CA5A | |
| SCHEMBL6026281 | 0.69 | KMT2A (0.42) | MEN1KMT2AALDH1A1THRBMAPT | |
| SCHEMBL6530524 | 0.68 | KMT2A (0.41) | MEN1KMT2AALDH1A1THRBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |